Inhibition of Replication of Chrondrocytes

Posted Fri, 02/06/2009 - 15:36 by FQHelp

Quinolone usage in children has been limited following the observation of arthrotoxicity in juvenile animals... The arthropathy evolves within days to weeks of drug administration... it is hypothesized that the effect of quinolones in some animal species may reflect inhibition of mitochondrial DNA replication in immature chondrocytes

— Allan R. Ronald, Don E. Low

Fluoroquinolone Antibiotics, Birkhäuser, 2003, ISBN 3764365919, 9783764365912

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- Pediatric Use
- Articles
- Research Sources
- Musculoskeletal Symptoms
- Side Effects
- DNA Damage

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