From my research, there is a definite correlation between the dosage and severity of adverse reactions.

First of all, the most important factor is dosage PER DAY. Someone who takes 750mg/day of Levaquin for 1 week, is far more likely to suffer a more severe adverse reaction than someone who takes 250mg/day of Levaquin for 3 weeks. As the dosage per day increases, the danger of suffering a serious reaction exponentially rises.

Through extensive analysis of reports on the internet regarding quinolone toxicity (more specifically that from Levaquin and Cipro), it seems that many side effects are usually either ones that are quite severe and happen immediately after the first dose, or delayed and occur days or weeks after the first dose. Below, a possible hypothesis to why this occurs is presented.

Levaquin or Cravit (Levofloxacin)

Levofloxacin, marketed as Levaquin or Cravit, is a third generation quinolone antibiotic. It was approved by the FDA on 1996, making it one of the newest quinolone antibiotics.

It is very effective against infections caused by Gram Positive and Gram Negative bacteria, but at what cost? Levaquin has been associated with serious side effects, that can be both debilitating and long term.