Symptoms affecting the musculoskeletal system, including tendon damage
Posted Fri, 02/06/2009 - 15:36 by FQHelp
Quinolone usage in children has been limited following the observation of arthrotoxicity in juvenile animals... The arthropathy evolves within days to weeks of drug administration... it is hypothesized that the effect of quinolones in some animal species may reflect inhibition of mitochondrial DNA replication in immature chondrocytes
— Allan R. Ronald, Don E. Low
Fluoroquinolone Antibiotics, Birkhäuser, 2003, ISBN 3764365919, 9783764365912
Posted Tue, 02/03/2009 - 19:17 by FQHelp
The fact that Cipro and quinolones can cause permanent, untreatable tendon damage as highlighted by the need for a black box warning, that leaves patients with crippling untreatable pain, is only the tip of the iceberg when it comes to the other severe and permanently disabling adverse reactions that Cipro and other quinolones can inflict. The product information sheets provided by quinolone manufacturers also fail to indicate that some individuals will suffer from multiple adverse reactions that will become permanent and untreatable.
— DBCipro, White Plains, NY
Posted Tue, 02/03/2009 - 19:01 by FQHelp
I took Levaquin in Feb. of 2008 and did not experience anything until April. It comes on quickly - pain in all joints, neuropathy, headaches plus a multitude of other problems. I understand it is a long and arduous road back. As for me - I would NEVER take any fluroquinolone again. The FDA has posted a "black box" warning on these medications. It has ruined my life.
Posted Mon, 02/02/2009 - 21:51 by FQHelp
The Chicago teen-ager was also 16 when a physician told her mother to give her Levaquin, according to the girl's sister.
The sister, Mrs. Teri Noto of Roselle, Ill., said the teen-ager did not get through the full course of daily 500-milligram Levaquin pills.
"After five days, it was as if a bomb went off in her body," said the sister. "She collapsed at school and had to be half-carried out of the building."
Posted Sat, 01/24/2009 - 22:11 by FQHelp
We observed ultrastructural changes in rat tendons several months after a single oral dose of a fluoroquinolone. I have no doubt what we found in rats corresponds to the clinical symptoms observed in patients during [fluoroquinolone] treatment.
Posted Thu, 01/22/2009 - 21:30 by FQHelp
I took Levaquin 2 months ago for a UTI. After the third dose, I went from a healthy 34 yr old to a 100 yr old woman. I had myalgia, extreme anxiety and panic, insomnia, tremors, neuropathy, tinnitus, blurred vision, and joint and tendon pain. Most of the symptoms have either diminished or gone away except for the joint and tendon pain, tinnitus, blurred vision, slight neuropathy, and some anxiety.
Posted Thu, 01/22/2009 - 21:25 by FQHelp
Within a day of stopping I had shooting pains down my legs, and my joints started hurting and cracking loudly when moved. I had constant muscle spasms, tightness and pain in my arms and legs that left me unable to leave the house for a week. I also developed a constant ringing in my ears for the first time in my life, which has not decreased since. Along with a host of other smaller symptoms.
Posted Thu, 01/22/2009 - 21:23 by FQHelp
On my 23rd birthday I started ciproI only took 3 doses of cipro in total before realizing what was happening… I went from being a very healthy 23 year old male who was athletic for over 10 years doing Karate, Yoga, Football, Judo and other sports, I eat an extremely healthy diet, no bad foods at all, and generally take care of myself in everyway possible, I have never drank alcohol and never smoked… I have all the blood tests and other tests to prove how healthy I was.
Posted Thu, 01/22/2009 - 21:19 by FQHelp
Fluoroquinolone antibiotics have damaged many people. I know of this severe damage on a personal level since I suffered such and adverse reaction to the fluoroquinolone antibiotic Levaquin myself 22 months ago. Since then I have had daily pain and disability of my nervous and musculoskeletal systems and for several months had endocrine and gastrointestinal problems as well.
Posted Thu, 01/22/2009 - 20:18 by FQHelp
We report two cases of tendon rupture associated with ciprofloxacin. One patient had a complete rupture of an Achilles tendon 6 months after taking the medication. The other case involved a partial rupture of the subscapularis tendon. Both ruptures occurred with minimal mechanical stress on the tendons, suggesting that the fluoroquinolone increased the susceptibility to rupture...
— J. Michael Casparian, MD, Michael Luchi, MD, Department of Medicine, University of Kansas
