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Articles regarding quinolones

Higher incidence of adverse reactions and side effects from levofloxacin (Levaquin)

Posted Thu, 01/22/2009 - 20:38 by FQHelp

Is Levofloxacin (Levaquin) more toxic than other quinolones?

Levofloxacin, a modified form of ofloxacin, is one of the most potent quinolones (about twice as potent as ofloxacin). Therefore, does levofloxacin exhibit a higher level of toxicity and rate of adverse reactions when compared to other fluoroquinolones?

 

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Adverse Effects Hypothesis: Mechanism of Toxicity

Posted Mon, 01/19/2009 - 18:43 by FQHelp

Through extensive analysis of reports on the internet regarding quinolone toxicity (more specifically that from Levaquin and Cipro), it seems that many side effects are usually either ones that are quite severe and happen immediately after the first dose, or delayed and occur days or weeks after the first dose. Below, a possible hypothesis to why this occurs is presented.

 

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Can clinical trials be distorted?

Posted Mon, 01/19/2009 - 17:57 by FQHelp

Reading through the drug insert of quinolones such as Levaquin shows that the incidence of side effects are very rare. That seems very strange, if you look at all those people suffering from quinolone toxicity.

According to Marcia Angell, not only can the incidence of side effects be distorted, but the effectiveness of the drug itself may also be distorted:

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Important articles regarding the side effects of quinolones

Posted Sun, 01/18/2009 - 21:55 by FQHelp

There are many articles that demonstrate the toxicity and risks of quinolones. Nevertheless, many doctors still believe that quinolones are a perfectly safe antibiotic, and may even prescribe them as first-line treatments for minor infections.

Even if you seek medical help for your serious side effects, very few doctors will actually believe you. Next time you visit another doctor, it would be a good idea to let them have a look at these reports below.

 

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Peripheral Neuropathy from Quinolones

Posted Sat, 01/17/2009 - 21:57 by FQHelp

Peripheral neuropathy, or damage to the peripheral nervous system is a listed side effect from fluoroquinolones such as Levaquin (levofloxacin) and Cipro (ciprofloxacin), to name a few. There are many reports of such damage becoming irreversible, and even worsening after treatment.

It's hard to imagine that an antibiotic can cause permanent damage and pain to anyone.

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